Hubei Nokete Pharmaceutical Co., Ltd.

Product Description: This product 14-Dehydro-11,12-didehydro-andrographolide -3,19-disuccinate half ester potassium sodium salt water. Molecular formula: C28H34KNaO10 · H2O

Product traits: This product is white or slightly yellow powder or lumps

Indications: This product has detoxification and antiviral effect, mainly for viral pneumonia and viral upper respiratory tract infection

Pharmacological effects:

The strains of Andrographis paniculata extract by esterification, dehydration, salt and refined from. Can inhibit the early increase in capillary permeability and inflammatory exudation and edema, can specifically stimulate the pituitary - adrenal cortex function, promote ACTH release, increase the anterior pituitary ACTH biosynthesis; in vitro with inactivated adenovirus, influenza Viruses, respiratory viruses and other viruses

Pharmacological experiments show that:

1, the goods caused by bacterial endotoxin in rabbits have a strong antipyretic effect, the role of rapid and can be maintained for more than 4 hours

2, the goods can be against the xylene or histamine caused by capillary wall permeability increased, and adrenaline acute pulmonary edema have a significant confrontation

3, this product can shorten the pentobarbital sodium-induced sleep latency, prolong its sleep time, but also to strengthen the role of subthreshold of pentobarbital sodium, causing the mice sleep, the results suggest that this product has obvious Sedative effect

4, the goods can significantly promote the rat adrenal cortical function, increase the body's ability to respond to pathogen infection

5, the clinical pathogen proof test and tissue culture inactivation test showed that the goods against influenza virus type Ⅰ, type Ⅲ, pneumonia adenovirus (Adv) type Ⅲ, Ⅳ type, intestinal syncytial virus and respiratory syncytial virus ( Rsv) are inactivated

Yanhuning less toxic, non-irritating, intravenous LD50 was 675mg / kg ± 30mg / kg